This theme is a discipline that applies engineering principles of design and analysis to biological systems and biomedical technologies. Examples of bioengineering research include bacteria engineered to produce chemicals, new medical imaging technology, portable disease diagnostic devices, and tissue engineered organs. Students in bioengineering are trained in fundamentals of both biology and engineering, which may include elements of electrical and mechanical engineering, computer science, materials science, chemistry, and biology.
E223: Radiopharmaceuticals: From Radiation Biophysics to the Clinic
E221: Joint Arthroplasty, Catheterization Interventions, and Tissue Engineering
This course is concerned with the impact of bio-chemical-mechanical behavior of biomaterials on various biotechnologies. The course provides insight into the biophysics of joints, catheterization, and scaffolding, and acquaints the participants with the current state-of-the-art procedures used in these fields and the challenges ahead.
E222: Molecular Imaging Methods for R&D and Clinical Trials of Emerging Molecular Therapies
This course is designed as an introduction to the growing world of molecular imaging in medicine and research. The current confluence of increased understanding of how genetic differences mitigate drug response, alongside substantial innovation in targeted molecular therapeutics including gene editing approaches, represents an inflection point for the use of molecular imaging. This course will provide individuals with fundamental understandings of medical imaging modalities that are used in both R&D and clinical settings. Building upon this framework, corresponding methods for targeted molecular imaging including contrast mechanisms and probe design will provide direct relevance to current needs for high throughput in vivo efficacy measurements. Quantitative methods for image analysis will be taught in the context of real world disease targeted applications using published data from recent clinical trials.
E224B: Introduction to Neurophysiology
The brain is the most spectacular yet most mysterious organ in our body. It controls every action we make, determines who we are and exceeds in its capacity any existing computer. The course will provide students with a detailed description of the basic principles of brain function, i.e., neurophysiology. The course will start from the cellular resolution and expand into a systems-wide view (such as vision, auditory, motor, memory systems) while underscoring shared neurophysiological principles. Furthermore, the course will provide students with real-life examples of clinical conditions that are associated with malfunctions in those systems as well as examples of solutions that were derived to treat physiological deficits in them.
E224C: Interface between Neurobiology and Neural Engineering
The interface of neurobiology and engineering is revolutionizing the academic and industry
worlds. This can be seen in the initiatives arising to encourage this development (e.g., the
Obama Brain Initiative) and the emergence of private philanthropy and entrepreneurship going
in that direction in the industry world (e.g., GoogleBrain, Neuralink, etc…). The goal of this
course is therefore to expose students interested in neuroscience and engineering to the
remarkable interface between them. To do so, the course will review the utilization,
development and implementation of neural engineering technologies and their application
towards both basic science and therapeutic approaches. At the completion of this course students will have obtained basic knowledge of neural engineering and neuroscience and in
particular, the beneficial interface between them in ongoing and upcoming global initiatives.
E224A: How the Brains of Animals Work?
All animals live very diverse and distinct lives and hence might have varying requirements from their brains. In this course we will delve into the mysteries of animal behavior and explore what is in their brains that allow them to function as optimally as they do. This course will provide students with an overview of the classical neuroethological approaches taken by neuroscientists to make the most foundational discoveries in the field of neuroscience (many of which have been subsequently awarded the Nobel prize). Students in this course will learn about the basic properties of brain function and how these are implemented in the nervous systems of a variety of species. Understanding these basic building blocks of brain function will provide students with an understanding of how a complex system, such as the brain, functions and could (if they wish) move on to implement these ideas and principles in a variety of technologies approaches (as is currently done throughout industry). Importantly, students will understand how to think of brain computations and enrich their knowledge in basic academic sciences. This way of thinking extends far beyond brain function and can have a positive impact on students’ creativity that would aid in any organization they end up working in.