This mini-course aims at providing basics of Data Science to students and professionals who need to work with and analyze a large volume of data. The base programming language is Matlab, but techniques taught, and topics covered can be coded in any programming language. The course is aimed at students and audience in engineering and science major, and therefore examples, assignments and the course project are from real life scenarios and engineering problems. The objective is to provide the audience with a set of important tools that are necessary in analyzing large data. No specific background knowledge is needed for this course. Specifically, this course is designed for those with no or little programming experience and background in data science.