The brain is the most spectacular yet most mysterious organ in our body. It controls every action we make, determines who we are and exceeds in its capacity any existing computer. The course will provide students with a detailed description of the basic principles of brain function, i.e., neurophysiology. The course will start from the cellular resolution and expand into a systems-wide view (such as vision, auditory, motor, memory systems) while underscoring shared neurophysiological principles. Furthermore, the course will provide students with real-life examples of clinical conditions that are associated with malfunctions in those systems as well as examples of solutions that were derived to treat physiological deficits in them.