E222: Molecular Imaging Methods for R&D and Clinical Trials of Emerging Molecular Therapies

This course is designed as an introduction to the growing world of molecular imaging in medicine and research. The current confluence of increased understanding of how genetic differences mitigate drug response, alongside substantial innovation in targeted molecular therapeutics including gene editing approaches, represents an inflection point for the use of molecular imaging. This course will provide individuals with fundamental understandings of medical imaging modalities that are used in both R&D and clinical settings. Building upon this framework, corresponding methods for targeted molecular imaging including contrast mechanisms and probe design will provide direct relevance to current needs for high throughput in vivo efficacy measurements. Quantitative methods for image analysis will be taught in the context of real world disease targeted applications using published data from recent clinical trials.